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81.
82.
We studied the impulse activity of neurons of the basal and lateral amygdalar nuclei generated when experimental animals (rats) performed fast stereotyped food-procuring movements by the forelimb. Within the basolateral amygdala, there are neurons whose activity is related to different stages of getting off the food, and according to the characteristics of their spiking these neurons should be divided into a number of subpopulations. Activation forestalling the movement initiation by 0.5-1.0 sec was observed in most neurons of the basolateral amygdala; this is considered a manifestation of excitation related to a motivation component of the food-procuring behavior. Activation of amygdalar neurons following movement initiation can result from generation in this structure of additional excitation necessary for successful performance of a complete food-procuring motor cycle. 相似文献
83.
A. A. Kepel' 《Russian Journal of Marine Biology》2000,26(6):450-452
The alga Analipus japonicus (Harv.) Wynne displays a distinct seasonal pattern in its development in Peter the Great Bay (Sea of Japan). In winter and spring, it occurs only in the form of basal crusts, and vertical axes develop in the summer–autumn period. It reproduces mostly asexually from July to November. Algae with unilocular sporangia occur very seldom, only in June and July. 相似文献
84.
85.
Binding of the cationic tetra(tributylammoniomethyl)-substituted hydroxoaluminum phthalocyanine (AlPcN4) to bilayer lipid membranes was studied by fluorescence correlation spectroscopy (FCS) and intramembrane field compensation (IFC) methods. With neutral phosphatidylcholine membranes, AlPcN4 appeared to bind more effectively than the negatively charged tetrasulfonated aluminum phthalocyanine (AlPcS4), which was attributed to the enhancement of the coordination interaction of aluminum with the phosphate moiety of phosphatidylcholine by the electric field created by positively charged groups of AlPcN4. The inhibitory effect of fluoride ions on the membrane binding of both AlPcN4 and AlPcS4 supported the essential role of aluminum-phosphate coordination in the interaction of these phthalocyanines with phospholipids. The presence of negative or positive charges on the surface of lipid membranes modulated the binding of AlPcN4 and AlPcS4 in accord with the character (attraction or repulsion) of the electrostatic interaction, thus showing the significant contribution of the latter to the phthalocyanine adsorption on lipid bilayers. The data on the photodynamic activity of AlPcN4 and AlPcS4 as measured by sensitized photoinactivation of gramicidin channels in bilayer lipid membranes correlated well with the binding data obtained by FCS and IFC techniques. The reduced photodynamic activity of AlPcN4 with neutral membranes violating this correlation was attributed to the concentration quenching of singlet excited states as proved by the data on the AlPcN4 fluorescence quenching. 相似文献
86.
The extent and nature of cyclic electron delocalization in free and coordinated cyclopropenylidene carbenes has been analyzed by combined experimental and theoretical charge-density studies. The significant asymmetry of the C-C bond lengths in substituted cyclopropenylidene carbenes was identified as cooperative effect which depends on contributions of both σ- and π-bonding. We show that analyses of (i) the topology of the Laplacian of the electron density distribution and (ii) the out-of-plane atomic quadrupole moments - the charge-density analogues of pπ occupation - allow to distinguish between the influence of σ- and π-electrons on cyclic electron delocalization. These studies hint for pronounced electron localization in the carbene lone pair region which dominates the electronic structure of free cyclopropenylidene carbenes and hinders the establishment of true aromaticity. We further investigated the electron donating/withdrawing ability of cyclopropenylidene ligands relative to N-heterocyclic carbenes. The experimental benchmark systems LCr(CO)5 (L = 2,3-diphenylcyclopropenylidene and 1,2-dimethylimidazol-2-ylidene) show that the cyclopropenylidene ligand clearly displays the higher π-acceptor capability relative to N-heterocyclic carbenes. 相似文献
87.
Josep C. Jiménez-Chillarón Rubén Díaz Débora Martínez Thais Pentinat Marta Ramón-Krauel Sílvia Ribó Torsten Plösch 《Biochimie》2012
Nutrition plays a key role in many aspects of health and dietary imbalances are major determinants of chronic diseases including cardiovascular disease, obesity, diabetes and cancer. Adequate nutrition is particularly essential during critical periods in early life (both pre- and postnatal). In this regard, there is extensive epidemiologic and experimental data showing that early sub-optimal nutrition can have health consequences several decades later. 相似文献
88.
89.
Larvae and nymphs of the tick Ixodes ricinus L. display similar reactions to analogs of the insect juvenile hormones (methoprene and pyriproxyfen), which induce at both stages juvenalization of the Haller's sense organ regenerates. Similar effects were also described for retinoic acid. Unlike juvenoids, retinoic acid can affect not only regeneration, but also normal development of the Haller's organ and cause changes corresponding to so-called regenerative induction. Amputation of the leg and treatment with retinoic acid do not affect the duration of larval or nymphal development, while juvenoids somewhat accelerate their development. 相似文献
90.
Gerda Saxer Michael Doebeli Michael Travisano 《Proceedings. Biological sciences / The Royal Society》2009,276(1664):2065-2070
Spatial structure has been identified as a major contributor to the maintenance of diversity. Here, we show that the impact of spatial structure on diversity is strongly affected by the ecological mechanisms maintaining diversity. In well-mixed, unstructured environments, microbial populations can diversify by production of metabolites during growth, providing additional resources for novel specialists. By contrast, spatially structured environments potentially limit such facilitation due to reduced metabolite diffusion. Using replicate microcosms containing the bacterium Escherichia coli, we predicted the loss of diversity during an environmental shift from a spatially unstructured environment to spatially structured conditions. Although spatial structure is frequently observed to be a major promoter of diversity, our results indicate that it can also have negative impacts on diversity. 相似文献